منابع مشابه
Genetics of vascular cognitive impairment: the opportunity and the challenges.
BACKGROUND AND PURPOSE This review considers the current state of knowledge of genetic factors underlying vascular cognitive impairment (VCI). SUMMARY OF REVIEW We argue here that genes conferring susceptibility to VCI must be of 2 nonmutually exclusive classes: (1) genes that confer susceptibility to cerebrovascular disease, and (2) genes that determine brain tissue responses to cerebrovascu...
متن کاملVascular cognitive impairment.
Dementia, a syndrome of declining higher cognitive functioning, found in approximately 10 per cent of adults 65 years and older, and 50 per cent of adults older than 90 years. Alzheimer’s disease (AD) accounts for 50 to 80 per cent of all dementing illnesses. Vascular dementia comprises 15 to 20 per cent of dementia and in some clinico-pathological series is the second commonest form of dementi...
متن کاملVascular Cognitive Impairment.
Cerebrovascular disease typically manifests with stroke, cognitive impairment, or both. Vascular cognitive impairment refers to all forms of cognitive disorder associated with cerebrovascular disease, regardless of the specific mechanisms involved. It encompasses the full range of cognitive deficits from mild cognitive impairment to dementia. In principle, any of the multiple causes of clinical...
متن کاملVascular Cognitive Impairment
The role of systemic vascular disease in the development and manifestation of dementing illnesses is becoming increasingly important. Both epidemiologic and histopathologic studies have emphasized the role of vascular risk factors not only in the development of cognitive impairment and dementia, but also in the cognitive dysfunction that may result in the presence of both vascular and neurodege...
متن کاملVascular Cognitive Impairment.
Although vascular dementia remains the only form of dementia that is preventable, available treatment is limited to the primary and secondary prevention of cerebrovascular disease. Strokes are highly responsive to different forms of prevention and treatment. The effectiveness of the same measures in the prevention of vascular dementia remains unclear, however, owing mainly to the lack of agreem...
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ژورنال
عنوان ژورنال: Stroke
سال: 2019
ISSN: 0039-2499,1524-4628
DOI: 10.1161/strokeaha.118.020379